The rare first separate edition of a landmark text on the therapeutic treatment of diabetes, offered complete in the publisher's original lemon wrappers, carefully restored and bound into attractive, modern buff cloth boards with mounted title label. It details 15 years of clinical studies, describing the first effective treatment for adult onset or Type 2 diabetes since Avicenna, based on meticulous attention to glucose levels in the patient's urine, a regimen of regular physical exercise and a nutritious and healthy low carbohydrate diet. CONDITION DETAIL: Pages: Professional conservation to the fragile leaves: the half-title page, title page and 22 other sheets have margin tears expertly repaired: bottom corner wear: soiling to extremities, otherwise clean except a few pages with trace soiling at fore-edge, and pp. 52-55 with scattered very small stain-spots in outer margin and a 2.5 cm margin stain, diminishing quickly-mostly light. Endpapers: Fine. Wrappers: soiled with bottom corner crease and some tiny top & bottom edge chips. Boards: About Fine. Binding: Excellent. FORMAT: Publisher's fragile lemon paper wrappers with black letters, title on upper, publisher's advertisements on lower, bound in buff cloth boards with mounted cream paper title slip with black letters, binding sewn with custom endpapers with rounded corners, matching wrappers rounded corners. SIZE: Wrappers: 280 x 225 mm (11.02 x 8.86 inches). Cloth Boards: 283 x 229 mm. Mounted title label: 98 x 74 mm. PAGINATION: Verified with OCLC 19021354 and Tome (Volume) 16 of Des Mémoires de L'Académie Nationale de Médicine, where it appears at pp. 69-212. Confirmed complete,  preliminary leaves, the half-title page, verso with 15 author publications published prior by the publisher and title page, verso blank + 144 pages, text with footnotes, no illustrations. Introduction: pp. 1-2; Section I: Pratiques sur la Glucosurie, pp. 3-62; Section II: Se Repportant a L'Etiologie de la Glucosuries, pp. 63-101; Section III: Du Traitement de la Glucosurie, pp. 102-126; Section IV: Partie Historique et Critique, pp. 127-140; List of Selected publications based on original research, p. 141; Note sur L'Utilisation, Du Sucre D'Inuline ou du Sucre Lévogyre par Les Glucosuriques, pp 142-144. BOUCHARDAT: French pharmacist and nutritionist; trained in organic chemistry at the Ecole de Pharmacie de Paris with advanced study at the Muséum d'Histoire Naturelle; chief pharmacist at the Hôtel Dieu in Paris from 1835 and from the 1850's, Professor of Hygiene (Public Health) on their faculty; early important study of fermentation and author of the influential, encyclopedic "Nouveau Formulaire Magistral"; began clinical studies of diabetes in 1835. After years of research and treatment of patients, the clinician of reference on diabetes until Elliot P. Joslin, who built on his findings. Bouchardat was the first to develop a clinically proven treatment for Type 2 Diabetes that effectively reduced glucose levels. His dietetic therapy included daily self-testing by patients of the glucose levels in their urine using the Trommer test, a regimen of physical exercise, and a low carbohydrate diet that unlike the recommended diet of fatty meats prescribed by the pioneering physician, John Rollo in, "An Account of Two Cases of the Diabetes Mellitus" (1798) was nutritionally balanced and palatable and sustainable. After 1871, based on his observations of the 1870 German siege of Paris, he advocated a low intake diet of the minimum calories required for sustenance. In 1875, he published his definitive text on the subject, "De La Glycosurie Ou Diabète Sucre", which included his observations on lesions in the pancreas. AVAILABILITY: A worldwide catalog search finds 6 institutional holdings including Yale, Stanford, and the University of Chicago. REFERENCE: Joslin et al, Joslin's Diabetes Mellitus, p. 3, authors praise Bouchardat's pioneering and "meticulous long-term studies on human diabetes". Standard bibliographical works record only the 1875 book: Garrison-Morton 3940; Hirsch I/646-47. ADDITIONAL IMAGES: by request.
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