Actinomycins

by Waksman, Selman A

Ex-Library

Price: $7.45
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Book desription: Interscience Publishers, 1968. Ex-Library. Hard Cover. Good/No Jacket. Minor shelf and cover edge wear, few ink notes in text, Only library mark is paper stamp on flypaper."Actinomycin-D is primarily used as an investigative tool in cell biology to inhibit transcription. It does this by binding DNA at the transcription initiation complex and preventing elongation by RNA polymerase. As it can bind DNA duplexes, it can also interfere with DNA replication, although other chemicals such as hydroxyurea are better suited for use in the laboratory as inhibitors of DNA synthesis. "--Wikipedia. Historical; Production and isolation; The chemistry of Actinomycin; the Biogenesis of the Actinomycins; The Effects of Actinomycin on Virus Replication; Actimonycin in Developmetnal biology; selective cytotoxicity of Actinomycin in Mammals; the Action of Actinomycin in experimental tumors; role of Actinomycin D; The Use of Actinomyin in Neopliastic Disease in Adults; Modification of the Immune Response by Actinomycin.

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