The Nucleus Unknown - 2010 - 1st Edition
by Tom Misteli
From the publisher
The nucleus of a cell contains its DNA and is the site where DNA replication, transcription, and RNA processing take place. Nuclei have many domains but lack the membrane-bound organelles characteristic of the cytoplasm. Instead, nuclear bodies appear to dynamically self-organize, assembling and disassembling according to the functional demands of the cell. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions discussing the relationship between nuclear structure and function, the various nuclear bodies that have been identified, and the organization of the nuclear lamina and nuclear pore complex. Other contributions examine the higher-order organization of chromatin within the nucleus and the dynamics of DNA replication, transcription, DNA repair, and RNA transport. Including a historical introduction to the field and discussion of the numerous pathological conditions involving disruption of nuclear structure and function, this volume is essential reading for all molecular and cell biologists, as well as pathologists interested in the role of nuclear architecture in disease.
Details
- Title The Nucleus
- Author Tom Misteli
- Binding unknown
- Edition number 1st
- Edition 1
- Pages 517
- Language ENG
- Publisher Cold Spring Harbor Laboratory Press, COLD SPRING HARBOR LABORATORY PRESS
- Date 2010-11
- ISBN 9780879698942
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