The HDL handbook; biological functions and clinical implications, 2d ed. by Ed. by Tsugikazu Komoda - 2014

Academic Press, 2014. Hardbound. New Book. Hardbound. Editor Komoda's research handbook for physicians and medical scientists addresses in detail the biochemistry and pathophysiology of high-density lipoprotein (HDL) cholesterol. The history of HDL research is summarized in the introduction, including its labeling as "good cholesterol" and recent questions problematizing that label. The ensuing chapters discuss apolipoprotein A-1 mutations, diversity of high-density lipoproteins, reverse cholesterol transport, ATP-binding cassette transporter A1 and G1, sphingolipids, lecithin and cholesterol acyltransferase, cholesteryl ester transfer protein inhibitors, apoprotein mimetic peptides, oxidized HDL, paraoxonase-1, and use of proteomics techniques in HDL research. Molecular biology of the discussed targets is linked to clinical outcomes and epidemiology. (2014 Ringgold, Inc., Portland, OR)