Mitosis. The Movements of Chromosomes in Cell Division.
by (Chargaff, Erwin) Schrader, Franz
- Used
- Hardcover
- Signed
- Condition
- See description
- Seller
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Moray, United Kingdom
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About This Item
New York, Morningside Heights: Columbia University Press, 1949. Octavo. Original blue cloth, titles to spine gilt. 1 double-sided plate, illustrations within the text. Very lightly rubbed at the tips, small blue sink spots on the upper edge of the text block. Excellent condition. Third printing of this influential work, originally published in 1944. From the library of molecular biologist Erwin Chargaff (1905-2002), with this ownership signature in ink on the front free endpaper. Chargaff's work elucidated key concepts about DNA and provided part of the groundwork for Watson and Crick's discovery of its structure. Chargaff's rules, as they are now known, state that the quantities of the four nucleotides are always linked - guanine matching that of cytosine and adenine with thiamine, and that the relative amounts of each vary from species to species. These observations strongly hinted that the nucleotides carried the genetic information (rather than the protein components, as had been thought previously), and, most importantly, that DNA could have a double structure - the key to the cell's ability to both read and replicate it. "Chargaff discussed the results at a tetchy meeting with Watson and Crick in May 1952, and later told Horace Judson, the historian of the discovery of DNA, that 'they impressed me by their extreme ignorance'" (Guardian obituary). Chargaff's contributions, along with those of Rosalind Franklin, were ignored by the Nobel Prize committee, leading to his bitterness in later life. The present text is a significant in our understanding of the physical processes involved in cell division. Franz Schrader (1891-1962) was a Columbia University cytologist who, in 1932, began studying spindles, the structures in cells that form during cell division and pull apart the copied chromosomes. Mitosis "placed what was known of these subjects under searching analysis and offered new directions for research on chromosomal movements" (Cooper, Franz Schrader: A Biographical Memoir, National Academy of Sciences, 1993). An excellent association.
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Details
- Bookseller
- Alembic Rare Books (GB)
- Bookseller's Inventory #
- 209
- Title
- Mitosis. The Movements of Chromosomes in Cell Division.
- Author
- (Chargaff, Erwin) Schrader, Franz
- Book Condition
- Used
- Quantity Available
- 1
- Binding
- Hardcover
- Publisher
- Columbia University Press
- Place of Publication
- New York, Morningside Heights
- Date Published
- 1949
- Keywords
- Science|Biology|DNA & Heredity|Molecular Biology|Cell Biology|Genetics
Terms of Sale
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About the Seller
Alembic Rare Books
Biblio member since 2018
Moray
About Alembic Rare Books
We specialise in rare science books dating from the late Middle Ages to the 20th century, including first editions, signed copies, manuscripts, objects, and ephemera. We have particular expertise in natural history, genetics and evolution, anatomy, nuclear physics and the Manhattan Project, early computing, and women in science. We also carry books related to women's history and literature.
Glossary
Some terminology that may be used in this description includes:
- Text Block
- Most simply the inside pages of a book. More precisely, the block of paper formed by the cut and stacked pages of a book....
- Spine
- The outer portion of a book which covers the actual binding. The spine usually faces outward when a book is placed on a shelf....
- Octavo
- Another of the terms referring to page or book size, octavo refers to a standard printer's sheet folded four times, producing...
- Plate
- Full page illustration or photograph. Plates are printed separately from the text of the book, and bound in at production. I.e.,...
- Cloth
- "Cloth-bound" generally refers to a hardcover book with cloth covering the outside of the book covers. The cloth is stretched...
- Gilt
- The decorative application of gold or gold coloring to a portion of a book on the spine, edges of the text block, or an inlay in...
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