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    Cutaneous Melanoma: Etiology and Therapy by William H. Ward, MD and Jeffrey M. Farma, MD

    Cutaneous Melanoma: Etiology and Therapy , edited by William H. Ward, MD and Jeffrey M. Farma, MD from Fox Chase Cancer Center, USA, gathers a diverse and accomplished group of authors with expertise in both clinical and scientific aspects of melanoma development, diagnosis, and treatment. An exhaustive review of the entire spectrum of cutaneous melanoma is presented, including its epidemiologic background, diagnostic strategies, updated treatment approaches, and long-term management. Many of the therapeutic options developed in recent years have generated newfound enthusiasm among clinicians caring for patients with advanced disease. However, proper workup at the time of initial diagnosis is paramount, and patient outcomes can definitively suffer if the appropriate staging is compromised. As such, clinicians involved in the diagnosis or treatment of cutaneous melanoma must be familiar with the importance of available screening options, methods of clinical or histologic diagnosis, and the staging ramifications of disease discovery. This book provides a robust review of each of these elements and is recommended to anyone involved in the study or treatment of cutaneous melanoma. The book, published by Codon Publications, Brisbane, Australia, will be a valuable resource for libraries, health care professionals, researchers and students. Specifications: Full color hardcover; Approximate dimensions: 16 cm (6.3 in) x 24 cm (9.4 in) x 1.5 cm (0.6 in); Number of Chapters: 11; Figures: 16; Tables: 12.



    Die krankhaften Geschwülste by Virchow, Rudolph

    Berlin: Hirschwald, 1863. In the Extremely Rare Original Wrappers Virchow, Rudolf (1821-1902). Die krankhaften Geschwülste. 3 vols. in 4 [all published]. Erster Band: xii, 543, [1]pp. plus 33-page publisher's catalogue; 1 plate. II. Band, 1. Hälfte: [2], 288pp. II. Band, 2. Hälfte: x, 289-756pp. III. Band, 1. Hälfte: [2], 496pp.; 1 plate. Text illustrations. Berlin: August Hirschwald, 1863-67. 245 x 170 mm. (uncut and partially unopened). Original printed wrappers, minor wear and chipping, spine of last volume partly split; preserved in cloth slipcase with chemises. Minor dampstaining, uncut edges a little frayed, a few signatures loose, pp. 106-7 in Vol. I with some offsetting from laid-in sheet of manuscript notes (see below). Very good set. From the library of Dutch surgeons Jan van der Hoeven (1834-1900) and his son Jan (1863-1941), with their signatures, dated 1863 and 1900 respectively, on the front wrapper of Vol. I; van der Hoeven bookplate in last volume; densely written sheet of manuscript notes in the hand of the first van der Hoeven laid in. First Edition, in the extremely rare original wrappers, of Virchow's highly influential work on morbid tumors-his "most ambitious literary undertaking" (Ackerknecht, Rudolph Virchow). "Tumors were perhaps Virchow's greatest interest, and in 1863 he began publication of what was to be a comprehensive treatise on the subject. It was never completed, for Virchow stopped when he reached the point where carcinoma was to be discussed, probably because of the vigorous attack which Remak and others were making on his conception of the histogenesis of epithelioma. Nevertheless this work remains one of the great source-books on cancer" (Haagensen, An Exhibit of Important Books Illustrating the Evolution of the Knowledge of Cancer, p. 80). "[Virchow's] works in the field of oncology have been of the most far-reaching importance. Although he himself did not deal with cancer in his famous work 'The morbid tumors,' which was left incomplete, we can nevertheless find in it his general opinions of tumors. . . . [H]e designated as homologous tumors the type whose tissue elements are those which form in places that normally contain the same kind of tissue; the heterologous tumors are those which form in a place where the typical tissue elements of the tumors normally do not occur. Thus, 'deviation from the type of the mother tissue' represented to Virchow the characteristic feature of malignant neoplasm. Virchow presented this anatomical and histological characteristic as the principal criterion for the classification of tumors. . . . "On the basis of these views Virchow, for the first time, and in a systematic manner, separated sarcomatous tumors from carcinomas. Sarcomas deviate little, structurally, from the typical structure of the different kinds of connective tissue, and distinguish themselves only by their great 'number of cells' and not by the 'form.' With this theory Virchow sought to eliminate the classification into benign and malignant tumors, which, though rather unscientific, had been commonly used by practitioners until that time" (Wolff, The Science of Cancerous Disease from Earliest Times to the Present, p. 185). Virchow's Die krankhaften Geschwülste, based on a series of lectures, is normally found bound in three volumes; it is extremely rare in the original four parts with their printed wrappers. This copy was once owned by the Jan van der Hoevens, father and son, both of whom practiced as surgeons in Leiden. Garrison-Morton 2617. Lindeboom, Dutch Medical Biography (for the van der Hoevens).



    Wilms Tumor by Marry M. van den Heuvel-Eibrink, MD, PhD

    Wilms tumor, contributed by 64 experts from around the globe, is intended to be a valuable resource for healthcare professionals, researchers and students who are interested in Wilms tumor research and/or the care of children with Wilms tumor or nephroblastoma. This book has three sections: Epidemiology, Diagnosis and Treatment; Biology; and WT1 Gene Aberrations in Other Malignancies. Epidemiology, diagnosis, and treatment: What are the challenges in diagnosis and treatment of Wilms tumor? What do we know about the long-term kidney function in Wilms tumor survivors? Nine chapters in this section give a comprehensive account of these challenges and strategies. The first three chapters give a very comprehensive account of prevalence and challenges in differential diagnosis of Wilms tumor and the importance of age in prognosis. This is followed by three chapters that discuss the surgical and other management strategies for unilateral, bilateral and extrarenal Wilms tumor. Of the remaining three chapters, two chapters provide an update on innovative neoadjuvant transcatheter and dendritic cell-based immunotherapy for the treatment of Wilms tumor. The last chapter provides an account of chronic kidney disease in Wilms tumor survivors. Biology: A faulty WT1 gene is the culprit in causing Wilms tumor. Three chapters in this section give an elegant account of how a faulty WT1 gene affects various cellular pathways and eventually lead to the initiation and progression of Wilms tumor. WT1 gene aberration in other malignancies: While a faulty WT1 gene is the reason for Wilms tumor, it may come as a surprise that it is also involved in other ailments. The four chapters in this section describe the role of WT1 in heart development, prostate cancer, brain tumors and acute myeloid leukemia. Specification: The book has 294 pages with 16 chapters, 50 figures, and 20 Tables. The approximate dimensions are 18.5 cm (7.3 in) x 26.5 cm (10.4 in) x 2.5 cm (1 in).



    Glioblastoma by Steven De Vleeschouwer MD PhD (Editor)

    Glioblastoma, contributed by 71 experts from around the globe, is intended to be a valuable resource for health care professionals, researchers and students who are dedicated to glioblastoma research and/or the care of patients with glioblastoma. The book has three sections: understanding glioblastoma in the lab, managing glioblastoma in the clinic, and upcoming cutting-edge innovations. Understanding glioblastoma in the lab: What causes glioblastoma, and how does it progress to be a deadly brain cancer? Seven chapters in this section give a very comprehensive understanding of how genetics, epigenetics, microRNA, cancer stem cells and glioma cell motility contribute to the genesis and progression of glioblastoma, and how they determine response of glioblastoma to treatment and clinical decision-making. Managing glioblastoma in the clinic: How is glioblastoma treated and what are the challenges? Here, oncologists, radiologists and neurosurgeons, discuss the diagnostic, therapeutic, and management challenges they face every day under the following headings: epidemiology; PET imaging options; PET tracers in assessing therapy response; current standard-of-care in glioblastoma therapy; surgical management; intraoperative cortical brain mapping; managing recurrent glioblastoma; and pediatric glioblastoma. Upcoming cutting edge innovations: What is the future of glioblastoma treatment? Direct access to the tumor is a big challenge for oncologists and neurosurgeons, and most drugs do not reach the tumor. One of the ways to overcome this inaccessibility is to maximize local drug delivery to the tumor. Six chapters of this section, describing innovative techniques to maximize access to therapeutic deliveries, if translated successfully, could create a paradigm shift in the treatment of glioblastoma. Specification: The book is full color, printed on 80gsm satin paper with 432 pages, 21 chapters, 64 figures and 24 tables. The approximate dimensions are 16 cm (6.3 in) x 24 cm (9.4 in) x 2.3 cm (0.90 in).



    Fundamentals of oncology by Henry C Pitot

    1981-01-01. Good. Ships with Tracking Number! INTERNATIONAL WORLDWIDE Shipping available. May not contain Access Codes or Supplements. May be ex-library. Shipping & Handling by region. Buy with confidence, excellent customer service!

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