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The Origins of Genome Architecture
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The Origins of Genome Architecture Hardcover - 2007 - 1st Edition

by Michael Lynch


From the publisher

With official genomic blueprints now available for hundreds of species, and thousands more expected in the near future, the field of biology has been forever transformed. Such readily accessible data have encouraged the proliferation of adaptive arguments for the evolution of gene and genomic features, often with little or no attention being given to simpler and more powerful alternative explanations. By integrating the central observations from molecular biology and population genetics relevant to comparative genomics, Lynch shows why the details matter. Presented in a nontechnical fashion, at both the population-genetic and molecular-genetic levels, this book offers a unifying explanatory framework for how the peculiar architectural diversity of eukaryotic genomes and genes came to arise. Under Lynch's hypothesis, the genome-wide repatterning of eukaryotic gene structure, which resulted primarily from nonadaptive processes, provided an entirely novel resource from which natural selection could secondarily build new forms of organismal complexity.

Details

  • Title The Origins of Genome Architecture
  • Author Michael Lynch
  • Binding Hardcover
  • Edition number 1st
  • Edition 1
  • Pages 512
  • Volumes 1
  • Language ENG
  • Publisher Sinauer Associates Is an Imprint of Oxford Un
  • Date 2007-03-03
  • Illustrated Yes
  • Features Bibliography, Illustrated, Index
  • ISBN 9780878934843 / 0878934847
  • Weight 2.45 lbs (1.11 kg)
  • Dimensions 7.4 x 9.7 x 1.2 in (18.80 x 24.64 x 3.05 cm)
  • Library of Congress Catalog Number 2007000012
  • Dewey Decimal Code 572.838

Media reviews

Citations

  • Scitech Book News, 09/01/2007, Page 57

About the author

Michael Lynch is Distinguished Professor of Biology at Indiana University. He received his B.S. in Biology from St. Bonaventure University, and his Ph.D. in Ecology from the University of Minnesota. Dr. Lynch has served as President of both the Society for the Study of Evolution and the American Genetic Association, and is a past council member of the Society for Molecular Biology and Evolution, and a fellow of the American Academy of Arts and Sciences. His research is focused on mechanisms of evolution at the gene, genomic, cellular, and phenotypic levels, with special attention being given to the roles of mutation, random genetic drift, and recombination.
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The Origins of Genome Architecture
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The Origins of Genome Architecture
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The Origins of Genome Architecture

by Michael Lynch

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by Michael Lynch

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