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Principles of CNS Drug Development: From Test Tube to Clinic and Beyond
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Principles of CNS Drug Development: From Test Tube to Clinic and Beyond Hardcover - 2010 - 1st Edition

by John Kelly

From the publisher

This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery. The book outlines the core processes in drug discovery and development for CNS disorders, from evaluating drugs for desirable efficacy, safety and pharmacokinetic features in preclinical (using in vitro and in vivo models) and clinical experimentation to identifying future drug targets. Containing up-to-date experimental evidence and detailing the main impediments in the pipeline of CNS drug discovery and development, this is a key reference for those involved in all stages of CNS drug discovery.

Key Features:

  • Discusses in detail the key stages of CNS drug discovery, outlining the particular requirements and obstacles for CNS drugs
  • Addresses safety concerns and future drug targets
  • Provides succinct background information about the major CNS diseases
  • Examples of specific drugs are used throughout to describe the development of a new drug from conception to clinical use and post-market surveillance
  • Primary reasons for drug failure are given for each stage

From the rear cover

Central Nervous System (CNS) disorders are responsible for a vast range of illnesses, including depression, schizophrenia, Parkinson's disease and Alzheimer's disease. Recent advances in areas such as genome sequencing and molecular biology have improved the potential for breakthrough treatments for these diseases, yet the drug development process for CNS disorders has remained stubbornly slow.

Principles of CNS Drug Development: From Test Tube to Patient outlines the core processes in drug discovery and development for CNS disorders, from evaluating drugs for desirable efficacy, safety and pharmacokinetic features in preclinical (using in vitro and in vivo models) and clinical experimentation to identifying future drug targets. Containing up-to-date experimental evidence and detailing the main impediments in the pipeline of CNS drug discovery and development, this is a key reference for those involved in all stages of CNS drug discovery.

  • Provides succinct background information on the major CNS diseases
  • Follows the development of a new drug from conception to clinical use and post-market surveillance using specific examples
  • Outlines the particular requirements and obstacles for CNS drugs
  • Highlights the primary reasons for drug failure at each stage
  • Addresses most likely future drug targets

Principles of CNS Drug Development: From Test Tube to Patient will be an invaluable resource for students, researchers and professionals in pharmacology, neuroscience and the pharmaceutical industry.

Details

  • Title Principles of CNS Drug Development: From Test Tube to Clinic and Beyond
  • Author John Kelly
  • Binding Hardcover
  • Edition number 1st
  • Edition 1
  • Pages 324
  • Volumes 1
  • Language ENG
  • Publisher Wiley
  • Date 2010-03
  • Illustrated Yes
  • Features Bibliography, Illustrated, Index, Table of Contents
  • ISBN 9780470519790 / 0470519797
  • Weight 1.5 lbs (0.68 kg)
  • Dimensions 9.8 x 6.7 x 0.9 in (24.89 x 17.02 x 2.29 cm)
  • Library of Congress subjects Drug development, Neuropharmacology
  • Library of Congress Catalog Number 2009041400
  • Dewey Decimal Code 615.78

Media reviews

Citations

  • Scitech Book News, 06/01/2010, Page 119

About the author

Dr. John Kelly, Senior Lecturer, Department of Pharmacology and Therapeutics, NUI, Galway, Ireland.
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Principles of CNS Drug Development: From Test Tube to Patient
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Principles of CNS Drug Development: From Test Tube to Clinic and Beyond

by Kelly, John

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Wiley. Hardcover. 0470519797 Good; Hardcover; Moderate wear to the covers; Clean textblock edges; Two creases to the right edge of 2nd endpaper; Text pages are bright & unmarked; Good binding with a straight spine; This book will be stored and delivered in a sturdy cardboard box with foam padding; Medium Format (8.5" - 9.75" tall); Blue covers with title in black lettering; 2010, John Wiley Publishing; 324 pages; "Principles of CNS Drug Development: From Test Tube to Clinic and Beyond," by John Kelly. . Good.
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